ABSTRACT
This study aimed to determine the shift in willingness regarding the COVID-19 vaccine after the second wave. The study attempts to understand the willingness towards COVID-19 vaccination by assessing the public's knowledge, concerns, and attitude regarding the vaccine. Between May 16 to May 28, 2021, the individuals of the general population were invited to fill the online questionnaire. Total 711 participants had given their informed consent and completed the questionnaire on their background and vaccination behavior-related variables such as knowledge, practices, and their concerns regarding the vaccine. Before the launching of the vaccine, people were less likely to get vaccinated (63.6%);however, once the second wave hit India, attitudes towards vaccines shifted dramatically, and the figure increased to 84.4%. A significant proportion of the population is now willing to take the vaccine. There are several socio-demographic differences regarding knowledge and concerns related to vaccines, especially in age and gender groups. The success of a COVID-19 vaccination program is determined not just by the vaccine's efficacy, but also by its uptake. To ensure optimum vaccination uptake, there is an immediate need for the most effective policy and communication. © 2021, Editorial board of Journal of Experimental Biology and Agricultural Sciences. All rights reserved.
ABSTRACT
Background: In Louisiana, deaths related to COVID-19 have disproportionately occurred in Black persons. Granular data are needed to better understand inequities and develop prevention strategies to mitigate further impact on Black communities. Methods: We conducted a retrospective cohort study of patients admitted to an urban safety net hospital in New Orleans, LA with reactive SARS-CoV-2 testing from March 9-31, 2020. Clinical characteristics and outcomes of Black and other racial/ethnic group patients were compared using Wilcoxon rank-sum test and Fisher's exact tests. We examined Day-14 status using an ordinal scale to assess race and outcome. Results: This study included 249 patients. Median age was 59, 44% were male, 86% were age ≥65 years or had ≥1 comorbidity. Overall, 87% were Black, relative to 55% Black patients typically hospitalized at our center. Black patients had longer symptom duration at presentation (6.41 versus 5.88 days, p=0.05), and were more likely to have asthma (p=0.008), but less likely to have dementia (p=0.002). There were no racial differences in initial respiratory status or laboratory values other than higher initial LDH in Black patients. Patient age and initial oxygen requirement, but not race (adjusted proportional odds ratio = 0.92, 95%CI: 0.70-1.20), were associated with worse Day-14 outcomes. Conclusion: Our results demonstrate minor racial differences in comorbidities or disease severity at presentation, and Day-14 outcomes were not different between groups. However, Black patients were disproportionately represented in hospitalizations, suggesting that prevention efforts should include strategies to limit SARS-CoV-2 exposures in Black communities as one step towards reducing racial inequities related to COVID-19. (Table Presented).
ABSTRACT
Background: In the 1960s, the human coronavirus was designated, which is responsible for the upper respiratory tract disease in children. Back in 2003, mainly 5 new coronaviruses were recognized. This study directly pursues to govern knowledge, attitude and practice of viral and drop-let infection isolation safeguard among the researchers during the outbreak of the COVID-19. Introduction: Coronavirus is a proteinaceous and infectious pathogen. It is an etiological agent of severe acute respiratory syndrome (SARS) and the Middle East respiratory syndrome (MERS). Coronavirus, appeared in China from the seafood and poultry market last year, which has spread in various countries, and has caused several deaths. Methods: The literature data has been taken from different search platforms like PubMed, Science Direct, Embase, Web of Science, who.int portal and complied. Results: Corona virology study will be more advanced and outstanding in recent years. COVID-19 epidemic is a threatening reminder not solely for one country but all over the universe. Conclusion: In this review article, we encapsulated the pathogenesis, geographical spread of coronavirus worldwide, also discussed the perspective of diagnosis, effective treatment, and primary recommendations by the World Health Organization, and guidelines of the government to slow down the impact of the virus are also optimistic, efficacious and obliging for the public health. However, it will take a prolonged time in the future to overcome this epidemic.